| Pair Name | Chrysin, Metformin | ||
| Phytochemical Name | Chrysin (PubChem CID: 5281607 ) | ||
| Anticancer drug Name | Metformin (PubChem CID: 4091 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Chrysin, Metformin | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Gene Regulation | Down-regulation | Expression | CCND1 | hsa595 |
| Down-regulation | Expression | TERT | hsa7015 | |
| In Vitro Model | T-47D | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0553 |
| Result | The conmbination of metformin and chrysin suppressing hTERT and cyclin D1 gene expression might offer an appropriate approach for breast cancer therapy. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells through hTERT and Cyclin D1 Suppression. Asian Pac J Cancer Prev. 2018 Apr 25;19(4):977-982. doi: 10.22034/APJCP.2018.19.4.977. | Click |
